Liam Byrne divides his time between making very old and very new music on the viola da gamba. He plays with many leading European early music ensembles including the Huelgas Ensembe, Dunedin Consort, Academy of Ancient Music, and Fretwork. Liam also works frequently with composers, folk musicians, and electronic musicians making new music with his 17th century instrument, such as Nico Muhly, Donnacha Dennehy, David Lang, Shara Nova, Efterklang, Martin Hayes, Valgeir Sigurðsson, Greg Saunier, Cleek Schrey, and many others. Liam has created sound installations for the Victoria & Albert museum, Dulwich Picture Gallery, and in collaboration with Nico Muhly for the National Gallery in London.
2017 saw the release of Tessellatum, a duo album with violist Nadia Sirota with music by Donnacha Dennehy, and Valgeir Sigurðsson's Dissonance, for which Liam co-authored the title track. He is a member of the Icelandic artist collective and record label Bedroom Community.